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Phenylen Brand names, Phenylen Analogs

Phenylen Brand Names Mixture

  • No information avaliable

Phenylen Chemical_Formula

C15H10O2

Phenylen RX_link

No information avaliable

Phenylen fda sheet

Phenylen msds (material safety sheet)

Phenylen MSDS

Phenylen Synthesis Reference

No information avaliable

Phenylen Molecular Weight

222.239 g/mol

Phenylen Melting Point

148-151 oC

Phenylen H2O Solubility

27 mg/L (at 20 oC)

Phenylen State

Solid

Phenylen LogP

2.917

Phenylen Dosage Forms

Tablet

Phenylen Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Phenylen Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Phenylen Absorption

Absorbed slowly from the gastrointestinal tract.

Phenylen side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Phenylen Patient Information

No information avaliable

Phenylen Organisms Affected

Humans and other mammals