Phenylacetamidopenicillanic Acid en es it fr

Phenylacetamidopenicillanic Acid Brand names, Phenylacetamidopenicillanic Acid Analogs

Phenylacetamidopenicillanic Acid Brand Names Mixture

  • No information avaliable

Phenylacetamidopenicillanic Acid Chemical_Formula

C16H18N2O4S

Phenylacetamidopenicillanic Acid RX_link

http://www.rxlist.com/cgi/generic3/pengk.htm

Phenylacetamidopenicillanic Acid fda sheet

Phenylacetamidopenicillanic Acid msds (material safety sheet)

Phenylacetamidopenicillanic_Acid MSDS

Phenylacetamidopenicillanic Acid Synthesis Reference

No information avaliable

Phenylacetamidopenicillanic Acid Molecular Weight

334.391 g/mol

Phenylacetamidopenicillanic Acid Melting Point

214-217oC

Phenylacetamidopenicillanic Acid H2O Solubility

Slightly soluble (210 mg/L)

Phenylacetamidopenicillanic Acid State

Solid

Phenylacetamidopenicillanic Acid LogP

1.212

Phenylacetamidopenicillanic Acid Dosage Forms

Powder for solution; Suspension; Tablet

Phenylacetamidopenicillanic Acid Indication

For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.

Phenylacetamidopenicillanic Acid Pharmacology

Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.

Phenylacetamidopenicillanic Acid Absorption

Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.

Phenylacetamidopenicillanic Acid side effects and Toxicity

Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.

Phenylacetamidopenicillanic Acid Patient Information

No information avaliable

Phenylacetamidopenicillanic Acid Organisms Affected

Enteric bacteria and other eubacteria