Phentolamine Mesylate en es it fr

Phentolamine Mesylate Brand names, Phentolamine Mesylate Analogs

Phentolamine Mesylate Brand Names Mixture

  • No information avaliable

Phentolamine Mesylate Chemical_Formula

C17H19N3O

Phentolamine Mesylate RX_link

http://www.rxlist.com/cgi/generic3/phentol.htm

Phentolamine Mesylate fda sheet

Phentolamine Mesylate msds (material safety sheet)

Phentolamine Mesylate Synthesis Reference

No information avaliable

Phentolamine Mesylate Molecular Weight

281.352 g/mol

Phentolamine Mesylate Melting Point

174.5 oC

Phentolamine Mesylate H2O Solubility

No information avaliable

Phentolamine Mesylate State

Solid

Phentolamine Mesylate LogP

2.551

Phentolamine Mesylate Dosage Forms

Liquid

Phentolamine Mesylate Indication

For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Phentolamine Mesylate Pharmacology

Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.

Phentolamine Mesylate Absorption

No information avaliable

Phentolamine Mesylate side effects and Toxicity

No information avaliable

Phentolamine Mesylate Patient Information

No information avaliable

Phentolamine Mesylate Organisms Affected

Humans and other mammals