Phentolamine Mesilate en es it fr

Phentolamine Mesilate Brand names, Phentolamine Mesilate Analogs

Phentolamine Mesilate Brand Names Mixture

  • No information avaliable

Phentolamine Mesilate Chemical_Formula

C17H19N3O

Phentolamine Mesilate RX_link

http://www.rxlist.com/cgi/generic3/phentol.htm

Phentolamine Mesilate fda sheet

Phentolamine Mesilate msds (material safety sheet)

Phentolamine Mesilate Synthesis Reference

No information avaliable

Phentolamine Mesilate Molecular Weight

281.352 g/mol

Phentolamine Mesilate Melting Point

174.5 oC

Phentolamine Mesilate H2O Solubility

No information avaliable

Phentolamine Mesilate State

Solid

Phentolamine Mesilate LogP

2.551

Phentolamine Mesilate Dosage Forms

Liquid

Phentolamine Mesilate Indication

For the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine. Also for the prevention or control of hypertensive episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision.

Phentolamine Mesilate Pharmacology

Phentolamine is indicated for the control of episodes of hypertension and sweating that occur with a disease called pheochromocytoma. If tachycardia is excessive, it may be necessary to use a beta-blocking agent concomitantly. Phentolamine is a long-acting, adrenergic, alpha-receptor blocking agent which can produce and maintain "chemical sympathectomy" by oral administration. It increases blood flow to the skin, mucosa and abdominal viscera, and lowers both supine and erect blood pressures. It has no effect on the parasympathetic system. Phentolamine works by blocking alpha receptors in certain parts of the body. Alpha receptors are present in the muscle that lines the walls of blood vessels. When the receptors are blocked by Phentolamine, the muscle relaxes and the blood vessels widen. This widening of the blood vessels results in a lowering of blood pressure.

Phentolamine Mesilate Absorption

No information avaliable

Phentolamine Mesilate side effects and Toxicity

No information avaliable

Phentolamine Mesilate Patient Information

No information avaliable

Phentolamine Mesilate Organisms Affected

Humans and other mammals