Phenmetrazine hydrochloride en es it fr

Phenmetrazine hydrochloride Brand names, Phenmetrazine hydrochloride Analogs

Phenmetrazine hydrochloride Brand Names Mixture

  • No information avaliable

Phenmetrazine hydrochloride Chemical_Formula

C11H15NO

Phenmetrazine hydrochloride RX_link

No information avaliable

Phenmetrazine hydrochloride fda sheet

Phenmetrazine hydrochloride msds (material safety sheet)

Phenmetrazine_hydrochloride MSDS

Phenmetrazine hydrochloride Synthesis Reference

No information avaliable

Phenmetrazine hydrochloride Molecular Weight

177.243 g/mol

Phenmetrazine hydrochloride Melting Point

139 oC

Phenmetrazine hydrochloride H2O Solubility

>5 mg/L

Phenmetrazine hydrochloride State

Solid

Phenmetrazine hydrochloride LogP

1.796

Phenmetrazine hydrochloride Dosage Forms

Tablet

Phenmetrazine hydrochloride Indication

Used as an anorectic in the treatment of obesity.

Phenmetrazine hydrochloride Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Phenmetrazine hydrochloride Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Phenmetrazine hydrochloride side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Phenmetrazine hydrochloride Patient Information

No information avaliable

Phenmetrazine hydrochloride Organisms Affected

Humans and other mammals