PharmacyCodes



Phenmetrazine en es it fr

Phenmetrazine Brand names, Phenmetrazine Analogs

Phenmetrazine Brand Names Mixture

  • No information avaliable

Phenmetrazine Chemical_Formula

C11H15NO

Phenmetrazine RX_link

No information avaliable

Phenmetrazine fda sheet

Phenmetrazine msds (material safety sheet)

Phenmetrazine MSDS

Phenmetrazine Synthesis Reference

No information avaliable

Phenmetrazine Molecular Weight

177.243 g/mol

Phenmetrazine Melting Point

139 oC

Phenmetrazine H2O Solubility

>5 mg/L

Phenmetrazine State

Solid

Phenmetrazine LogP

1.796

Phenmetrazine Dosage Forms

Tablet

Phenmetrazine Indication

Used as an anorectic in the treatment of obesity.

Phenmetrazine Pharmacology

Phenmetrazine is a sympathomimetic drug used primarily as an appetite depressant. Its actions and mechanisms are similar to dextroamphetamine. Amphetamines are non-catecholamine sympathomimetic amines with CNS stimulant activity. Phenmetrazine was originally sold under the tradename Preludin as an anorectic. It has since been removed from the market. It is by some considered to have a greater potential for addiction than the amphetamines, and has been abused in many countries, for example Sweden.

Phenmetrazine Absorption

Readily absorbed from the gastro-intestinal tract and buccal mucosa.

Phenmetrazine side effects and Toxicity

Adult monkeys have an LD50 of 15 to 20 mg/kg, whereas for young monkeys the LD50 is only 5 mg/kg. Symptoms of overdose include acute central nervous system stimulation, cardiotoxicity causing tachycardia, arrhythmias, hypertension, and cardiovascular collapse. Whilst some patients show signs of toxicity at blood concentrations of 20 µg/L, chronic abusers of amphetamine have been known to have blood concentration of up to 3000 µg/L.

Phenmetrazine Patient Information

No information avaliable

Phenmetrazine Organisms Affected

Humans and other mammals