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Phenemal Brand names, Phenemal Analogs

Phenemal Brand Names Mixture

  • No information avaliable

Phenemal Chemical_Formula

C12H12N2O3

Phenemal RX_link

No information avaliable

Phenemal fda sheet

Phenemal msds (material safety sheet)

Phenemal MSDS

Phenemal Synthesis Reference

Hoerlein, U.S. Pat. 1,025,872 (1912)

Phenemal Molecular Weight

232.235 g/mol

Phenemal Melting Point

174 oC

Phenemal H2O Solubility

<0.01 g/100 mL

Phenemal State

Solid

Phenemal LogP

1.777

Phenemal Dosage Forms

Tablet; Elixir

Phenemal Indication

For the treatment of Epilepsy

Phenemal Pharmacology

Phenobarbital, the longest-acting barbiturate, is used for its anticonvulsant and sedative-hypnotic properties in the management of all seizure disorders except absence (petit mal).

Phenemal Absorption

Absorbed in varying degrees following oral, rectal or parenteral administration. The salts are more rapidly absorbed than are the acids. The rate of absorption is increased if the sodium salt is ingested as a dilute solution or taken on an empty stomach

Phenemal side effects and Toxicity

CNS and respiratory depression which may progress to Cheyne-Stokes respiration, areflexia, constriction of the pupils to a slight degree (though in severe poisoning they may wshow paralytic dilation), oliguria, tachycardia, hypotension, lowered body temperature, and coma. Typical shock syndrome (apnea, circulatory collapse, respiratory arrest, and death) may occur.

Phenemal Patient Information

PATIENT INFORMATION

Practitioners should give the following information and instructions to patients receiving barbiturates:

1. The use of phenobarbital carries with it an associated risk of psychological and/or physical dependence.
The patient should be warned against increasing the dose of the drug without consulting a physician.

2. Phenobarbital may impair mental and/or physical abilities required for the performance of potentially
hazardous tasks (e.g., driving, operating machinery, etc.).

3. Alcohol should not be consumed while taking phenobarbital. Concurrent use of phenobarbital with other
CNS depressants (e.g., alcohol, narcotics, tranquilizers, and antihistamines) may result in additional CNS
depressant

Phenemal Organisms Affected

Humans and other mammals