Pfizer 1393
Pfizer 1393 Brand names, Pfizer 1393 Analogs
Pfizer 1393 Brand Names Mixture
- No information avaliable
Pfizer 1393 Chemical_Formula
C15H14ClN3O4S3
Pfizer 1393 RX_link
No information avaliable
Pfizer 1393 fda sheet
Pfizer 1393 msds (material safety sheet)
Pfizer 1393 Synthesis Reference
No information avaliable
Pfizer 1393 Molecular Weight
431.94 g/mol
Pfizer 1393 Melting Point
231.5 oC
Pfizer 1393 H2O Solubility
8.91 mg/L
Pfizer 1393 State
Solid
Pfizer 1393 LogP
2.918
Pfizer 1393 Dosage Forms
Tablet
Pfizer 1393 Indication
For the treatment of high blood pressure and management of edema.
Pfizer 1393 Pharmacology
Benzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also cause loss of potassium and an increase in serum uric acid. Thiazides are often used to treat hypertension, but their hypotensive effects are not necessarily due to their diuretic activity. Thiazides have been shown to prevent hypertension-related morbidity and mortality although the mechanism is not fully understood. Thiazides cause vasodilation by activating calcium-activated potassium channels (large conductance) in vascular smooth muscles and inhibiting various carbonic anhydrases in vascular tissue.
Pfizer 1393 Absorption
Absorbed in the digestive tract.
Pfizer 1393 side effects and Toxicity
Symptoms of overdose include nausea, vomiting, fatigue, urinary problems and drowsiness.
Pfizer 1393 Patient Information
Pfizer 1393 Organisms Affected
Humans and other mammals
