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Pethidine Brand names, Pethidine Analogs

Pethidine Brand Names Mixture

  • No information avaliable

Pethidine Chemical_Formula

C15H21NO2

Pethidine RX_link

http://www.rxlist.com/cgi/generic/meper.htm

Pethidine fda sheet

Pethidine FDA

Pethidine msds (material safety sheet)

Pethidine MSDS

Pethidine Synthesis Reference

No information avaliable

Pethidine Molecular Weight

247.333 g/mol

Pethidine Melting Point

186 - 189 oC

Pethidine H2O Solubility

3220 mg/L

Pethidine State

Solid

Pethidine LogP

3.303

Pethidine Dosage Forms

Syrup; Tablet

Pethidine Indication

Used to control moderate to severe pain.

Pethidine Pharmacology

Meperidine is a synthetic opiate agonist belonging to the phenylpiperidine class. Meperidine may produce less smooth muscle spasm, constipation, and depression of the cough reflex than equivalent doses of morphine. The onset of action is lightly more rapid than with morphine, and the duration of action is slightly shorter. The chemical structure of meperidine is similar to local anesthetics. Meperidine is recommended for relief of moderate to severe acute pain and has the unique ability to interrupt postoperative shivering and shaking chills induced by amphotericin B. Meperidine has also been used for intravenous regional anesthesia, peripheral nerve blocks and intraarticular, epidural and spinal analgesia. Meperidine is considered a second-line agent for the treatment of acute pain.

Pethidine Absorption

Oral bioavailability is 50-60% in patients with normal hepatic function.

Pethidine side effects and Toxicity

No information avaliable

Pethidine Patient Information

No information avaliable

Pethidine Organisms Affected

Humans and other mammals