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Permapen Brand names, Permapen Analogs

Permapen Brand Names Mixture

  • No information avaliable

Permapen Chemical_Formula

C16H18N2O4S

Permapen RX_link

http://www.rxlist.com/cgi/generic3/pengk.htm

Permapen fda sheet

Permapen msds (material safety sheet)

Permapen MSDS

Permapen Synthesis Reference

No information avaliable

Permapen Molecular Weight

334.391 g/mol

Permapen Melting Point

214-217oC

Permapen H2O Solubility

Slightly soluble (210 mg/L)

Permapen State

Solid

Permapen LogP

1.212

Permapen Dosage Forms

Powder for solution; Suspension; Tablet

Permapen Indication

For use in the treatment of severe infections caused by penicillin G-susceptible microorganisms when rapid and high penicillin levels are required.

Permapen Pharmacology

Penicillin G is a penicillin beta-lactam antibiotic used in the treatment of bacterial infections caused by susceptible, usually gram-positive, organisms. The name "penicillin" can either refer to several variants of penicillin available, or to the group of antibiotics derived from the penicillins. Penicillin G has in vitro activity against gram-positive and gram-negative aerobic and anaerobic bacteria. The bactericidal activity of penicillin G results from the inhibition of cell wall synthesis and is mediated through penicillin G binding to penicillin binding proteins (PBPs). Penicillin G is stable against hydrolysis by a variety of beta-lactamases, including penicillinases, and cephalosporinases and extended spectrum beta-lactamases.

Permapen Absorption

Rapidly absorbed following both intramuscular and subcutaneous injection. Initial blood levels following parenteral administration are high but transient.

Permapen side effects and Toxicity

Oral LD50 in rat is 8900 mk/kg. Neurological adverse reactions, including convulsions, may occur with the attainment of high CSF levels of beta-lactams.

Permapen Patient Information

No information avaliable

Permapen Organisms Affected

Enteric bacteria and other eubacteria