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Periplum Brand names, Periplum Analogs

Periplum Brand Names Mixture

  • No information avaliable

Periplum Chemical_Formula

C21H26N2O7

Periplum RX_link

http://www.rxlist.com/cgi/generic2/nimodip.htm

Periplum fda sheet

Periplum FDA

Periplum msds (material safety sheet)

Periplum Synthesis Reference

No information avaliable

Periplum Molecular Weight

418.44 g/mol

Periplum Melting Point

No information avaliable

Periplum H2O Solubility

No information avaliable

Periplum State

Solid

Periplum LogP

3.152

Periplum Dosage Forms

Capsules

Periplum Indication

For the treatment of subarachnoid bleeding.

Periplum Pharmacology

Nimodipine belongs to the class of pharmacological agents known as calcium channel blockers. Nimodipine is indicated for the improvement of neurological outcome by reducing the incidence and severity of ischemic deficits in patients with subarachnoid hemorrhage from ruptured congenital aneurysms who are in good neurological condition post-ictus (e.g., Hunt and Hess Grades I-III). The contractile processes of smooth muscle cells are dependent upon calcium ions, which enter these cells during depolarization as slow ionic transmembrane currents. Nimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscle. In animal experiments, nimodipine had a greater effect on cerebral arteries than on arteries elsewhere in the body perhaps because it is highly lipophilic, allowing it to cross the blood brain barrier.

Periplum Absorption

No information avaliable

Periplum side effects and Toxicity

No information avaliable

Periplum Patient Information

No information avaliable

Periplum Organisms Affected

Humans and other mammals