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Periostat Brand names, Periostat Analogs

Periostat Brand Names Mixture

  • No information avaliable

Periostat Chemical_Formula

C22H24N2O8

Periostat RX_link

http://www.rxlist.com/cgi/generic/doxycyc.htm

Periostat fda sheet

Periostat FDA

Periostat msds (material safety sheet)

Periostat MSDS

Periostat Synthesis Reference

C. R. Stephens et al.; J. Am. Chem. Soc. 80; 5324 (1958)

Periostat Molecular Weight

444.435 g/mol

Periostat Melting Point

201 oC

Periostat H2O Solubility

630 mg/L

Periostat State

Solid

Periostat LogP

-1.219

Periostat Dosage Forms

Tablet; Capsule; Gel; Liquid; Powder; Powder for solution

Periostat Indication

For the treatment of the following infections:Rocky mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by Rickettsiae, Chancroid caused by Haemophilus ducreyi, Uncomplicated gonorrhea caused by Neisseria gonorrhoeae, Respiratory tract infections caused by Mycoplasma pneumoniae or Streptococcus pneumoniae. Lymphogranuloma ve

Periostat Pharmacology

Doxycycline, a long-acting tetracycline derived from oxytetracycline, is used to inhibit bacterial protein synthesis and treat non-gonococcal urethritis and cervicitis, exacerbations of bronchitis in patients with COPD, and adult periodontitis.

Periostat Absorption

completely absorbed after oral administration

Periostat side effects and Toxicity

anorexia, nausea, diarrhoea, glossitis, dysphagia, enterocolitis and inflammatory lesions (with monilial overgrowth) in the anogenital region. skin reactions such as maculopapular and erythematous rashes, exfoliative dermatitis, photosensitivity, hypersensitivity reactions such as urticaria, angioneurotic oedema, anaphylaxis, anaphyl-actoid purpura, pericarditis, and exacerbation of systemic lupus erythematosus, benign intracranial hypertension in adults disappearing on discontinuation of the medicine, haematologic abnormalities such as haemolytic anaemia, thrombocytopenia, neutropenia, and eosinophilia. LD50=262 mg/kg(i.p. in rat)

Periostat Patient Information

Periostat Organisms Affected

Enteric bacteria and other eubacteria