Parnate

• Anti-anxiety Agents
• Antidepressants
• ATC:N06AF04

• Dl-Tranylcypromine
• Parnate
• Transamine

• No information avaliable

C₉H₁₁N

http://www.rxlist.com/cgi/generic2/tranylcypromine.htm

Parnate FDA

Parnate MSDS

No information avaliable

133.19 g/mol

79-80 ^oC at 1.50E+00 mm Hg

4.86E+004 mg/L

Solid

1.434

Tablets (10 mg, for oral administration)

For the treatment of major depressive episode without melancholia.

Tranylcypromine belongs to a class of antidepressants called monoamine oxidase inhibitors (MAOIs). Tranylcypromine is a non-hydrazine monoamine oxidase inhibitor with a rapid onset of activity. It increases the concentration of epinephrine, norepinephrine, and serotonin in storage sites throughout the nervous system and, in theory, this increased concentration of monoamines in the brain stem is the basis for its antidepressant activity.

No information avaliable

In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.

Humans and other mammals