Pantok
Pantok Brand names, Pantok Analogs
Pantok Brand Names Mixture
- No information avaliable
Pantok Chemical_Formula
C25H38O5
Pantok RX_link
http://www.rxlist.com/cgi/generic/simva.htm
Pantok fda sheet
Pantok msds (material safety sheet)
Pantok Synthesis Reference
W. F. Hoffman et al., U.S. Pat. 4,444,784 (1984)
Pantok Molecular Weight
418.566 g/mol
Pantok Melting Point
135-138oC
Pantok H2O Solubility
0.76 mg/L
Pantok State
Solid
Pantok LogP
4.937
Pantok Dosage Forms
Tablet (oral)
Pantok Indication
For the treatment of hypercholesterolemia.
Pantok Pharmacology
Simvastatin, the methylated form of lovastatin, is an oral antilipemic agent which inhibits HMG-CoA reductase. simvastatin is used in the treatment of primary hypercholesterolemia and is effective in reducing total and LDL-cholesterol as well as plasma triglycerides and apolipoprotein B.
Pantok Absorption
Absorption of simvastatin, estimated relative to an intravenous reference dose, in each of two animal species tested, averaged about 85% of an oral dose. In animal studies, after oral dosing, simvastatin achieved substantially higher concentrations in the liver than in non-target tissues.
Pantok side effects and Toxicity
No information avaliable
Pantok Patient Information
Patients should be advised about substances they should not take concomitantly with simvastatin and be advised to report promptly unexplained muscle pain, tenderness, or weakness. Patients should also be advised to inform other physicians prescribing a new medication that they are taking ZOCOR.
Pantok Organisms Affected
Humans and other mammals
