Pancrelipase
Pancrelipase Brand names, Pancrelipase Analogs
Pancrelipase Brand Names Mixture
- No information avaliable
Pancrelipase Chemical_Formula
C5850H8902N1606O1739S49
Pancrelipase RX_link
http://www.rxlist.com/cgi/generic2/pancrel.htm
Pancrelipase fda sheet
Pancrelipase msds (material safety sheet)
Pancrelipase Synthesis Reference
No information avaliable
Pancrelipase Molecular Weight
131125.6
Pancrelipase Melting Point
48-50 oC (Vinogradov, A.A. et al., Protein Eng. 14:683-689 (2001)).
Pancrelipase H2O Solubility
No information avaliable
Pancrelipase State
Liquid
Pancrelipase LogP
No information avaliable
Pancrelipase Dosage Forms
Tablet
Pancrelipase Indication
For treatment of cystic fibrosis, chronic pancreatitis, pancreatic duct blockage
Pancrelipase Pharmacology
Used in the treatment of cystic fibrosis or pancreatic dysfunction, pancrelipase helps improve fat digestion in the small intestine. Specifically, the lipase, protease and amylase components break down fat, protein, and starches, respectively, in the small intestine. Lipase hydrolyzes fats into glycerol and fatty acids. Protease converts proteins into proteoses and derived substances, while amylase converts starches into dextrins and sugars. Pancreatic enzymes are used to correct maldigestion, malabsorption and pain associated with pancreatic insufficiency. The major maldigestion/malabsorption problems arise from incomplete fat digestion. Exogenous pancrelipase reduces the amount of nitrogen and fat excreted in the stool.
Pancrelipase Absorption
No information avaliable
Pancrelipase side effects and Toxicity
No information avaliable
Pancrelipase Patient Information
No information avaliable
Pancrelipase Organisms Affected
Humans and other mammals
