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Oxomemazine Brand names, Oxomemazine Analogs

Oxomemazine Brand Names Mixture

  • Vanectyl-P Tablets (Prednisolone + Trimeprazine Tartrate)

Oxomemazine Chemical_Formula

C18H22N2S

Oxomemazine RX_link

No information avaliable

Oxomemazine fda sheet

Oxomemazine msds (material safety sheet)

Oxomemazine Synthesis Reference

No information avaliable

Oxomemazine Molecular Weight

298.447 g/mol

Oxomemazine Melting Point

68 oC

Oxomemazine H2O Solubility

0.942 mg/L

Oxomemazine State

Solid

Oxomemazine LogP

5.162

Oxomemazine Dosage Forms

Tablet (2.5 mg); Syrup (2.5 mg/5mL); Capsule(5 mg)

Oxomemazine Indication

Used to prevent and relieve allergic conditions which cause pruritus (itching) and urticaria (some allergic skin reactions).

Oxomemazine Pharmacology

Trimeprazine (also known as Alimemazine) is a tricyclic antihistamine, similar in structure to the phenothiazine antipsychotics, but differing in the ring-substitution and chain characteristics. Trimeprazine is in the same class of drugs as chlorpromazine (Thorazine) and trifluoperazine (Stelazine); however, unlike the other drugs in this class, trimeprazine is not used clinically as an anti-psychotic. It acts as an anti-histamine, a sedative, and an anti-emetic (anti-nausea). Trimeprazine is used principally as an anti-emetic, to prevent motion sickness or as an anti-histamine in combination with other medications in cough and cold preparations. Tricyclic antihistamines are also structurally-related to the tricyclic antidepressants, explaining the antihistaminergic adverse effects of these two drug classes and also the poor tolerability profile of tricyclic H1-antihistamines.

Oxomemazine Absorption

Well absorbed in the digestive tract.

Oxomemazine side effects and Toxicity

Symptoms of overdose clumsiness or unsteadiness, seizures, severe drowsiness, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath, shuffling walk, tic-like (jerky) movements of head and face, trembling and shaking of hands, and insomnia.

Oxomemazine Patient Information

Prescriber should notify the patient to report an form of confusion, sedation, or hypotension. Inform the patient to avoid driving and other hazardous activity if drowsiness occurs. Also inform the patient to avoid alcohol and other CNS depressants while on trimeprazine.

Oxomemazine Organisms Affected

Humans and other mammals