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Orgalutran Brand names, Orgalutran Analogs

Orgalutran Brand Names Mixture

  • No information avaliable

Orgalutran Chemical_Formula

C55H75N17O13

Orgalutran RX_link

http://www.rxlist.com/cgi/generic2/gonadorelin.htm

Orgalutran fda sheet

Orgalutran msds (material safety sheet)

Orgalutran MSDS

Orgalutran Synthesis Reference

No information avaliable

Orgalutran Molecular Weight

1182.29 g/mol

Orgalutran Melting Point

No information avaliable

Orgalutran H2O Solubility

1 mg/mL

Orgalutran State

Liquid

Orgalutran LogP

-4.634

Orgalutran Dosage Forms

Liquid; Powder for solution; Solution for infusion pump

Orgalutran Indication

For evaluating the functional capacity and response of the gonadotropes of the anterior pituitary also for evaluating residual gonadotropic function of the pituitary following removal of a pituitary tumor by surgery and/or irradiation.

Orgalutran Pharmacology

Gonadorelin is responsible for the release of follicle stimulating hormone and leutinizing hormone from the anterior pitutitary. In the pituitary GnRH stimulates synthesis and release of FSH and LH, a process that is controlled by the frequency and amplitude of GnRH pulses, as well as the feedback of androgens and estrogens. The pulsatility of GnRH secretion has been seen in all vertebrates, and it is necessary to ensure a correct reproductive function. Thus a single hormone, GnRH, controls a complex process of follicular growth, ovulation, and corpus luteum maintenance in the female, and spermatogenesis in the male. Its short half life requires infusion pumps for its clinical use

Orgalutran Absorption

Rapidly absorbed when injected

Orgalutran side effects and Toxicity

LD50>3000 mg/kg (rat, oral)

Orgalutran Patient Information

Orgalutran Organisms Affected

Humans and other mammals