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Ontak (Seragen Inc) Brand names, Ontak (Seragen Inc) Analogs

Ontak (Seragen Inc) Brand Names Mixture

  • No information avaliable

Ontak (Seragen Inc) Chemical_Formula

C2560H4042N678O799S17

Ontak (Seragen Inc) RX_link

http://www.rxlist.com/cgi/generic2/denileukin.htm

Ontak (Seragen Inc) fda sheet

Ontak (Seragen Inc) msds (material safety sheet)

Ontak (Seragen Inc) Synthesis Reference

No information avaliable

Ontak (Seragen Inc) Molecular Weight

57647.3

Ontak (Seragen Inc) Melting Point

No information avaliable

Ontak (Seragen Inc) H2O Solubility

No information avaliable

Ontak (Seragen Inc) State

Liquid

Ontak (Seragen Inc) LogP

-0.301

Ontak (Seragen Inc) Dosage Forms

Solution (IV Infusion)

Ontak (Seragen Inc) Indication

For treatment of cutaneous T-cell lymphoma

Ontak (Seragen Inc) Pharmacology

Denileukin diftitox (Ontak) directs the cytocidal action of diphtheria toxin to cells which express the IL-2 receptor. The human IL-2 receptor exists in three forms, low (CD25), intermediate (CD122/CD132) and high (CD25/CD122/CD132) affinity. Malignant cells expressing one or more of the subunits of the IL-2 receptor are found in certain leukemias and lymphomas including cutaneous T-cell lymphoma (CTCL). Ontak interacts with the high affinity IL-2 receptor on the cell surface and inhibits cellular protein synthesis, resulting in cell death within hours.

Ontak (Seragen Inc) Absorption

No information avaliable

Ontak (Seragen Inc) side effects and Toxicity

No information avaliable

Ontak (Seragen Inc) Patient Information

No information avaliable

Ontak (Seragen Inc) Organisms Affected

Humans and other mammals