Olmesartan medoximil
Olmesartan medoximil Brand names, Olmesartan medoximil Analogs
Olmesartan medoximil Brand Names Mixture
- No information avaliable
Olmesartan medoximil Chemical_Formula
C29H30N6O6
Olmesartan medoximil RX_link
http://www.rxlist.com/cgi/generic/benicar.htm
Olmesartan medoximil fda sheet
Olmesartan medoximil msds (material safety sheet)
Olmesartan medoximil Synthesis Reference
No information avaliable
Olmesartan medoximil Molecular Weight
558.585 g/mol
Olmesartan medoximil Melting Point
175-180 oC
Olmesartan medoximil H2O Solubility
No information avaliable
Olmesartan medoximil State
Solid
Olmesartan medoximil LogP
5.202
Olmesartan medoximil Dosage Forms
Tablet
Olmesartan medoximil Indication
For the treatment of hypertension
Olmesartan medoximil Pharmacology
Olmesartan Medoxomil, a specific angiotensin II type 1 antagonist, is used alone or with other antihypertensive agents to treat hypertension. Unlike the angiotensin receptor antagonist losartan, olmesartan does not have an active metabolite or possess uricosuric effects. Blockade of the angiotensin II receptor inhibits the negative regulatory feedback of angiotensin II on renin secretion, but the resulting increased plasma renin activity and circulating angiotensin II levels do not overcome the effect of olmesartan on blood pressure.
Olmesartan medoximil Absorption
Bioavailability is about 26%. Food does not affect the bioavailability of olmesartan.
Olmesartan medoximil side effects and Toxicity
Symptoms of overdose include dehydration (dry mouth, excessive thirst, muscle pain or cramps, nausea and vomiting, weakness), dizziness, low blood pressure, and slow or irregular heartbeat.
Olmesartan medoximil Patient Information
Olmesartan medoximil Organisms Affected
Humans and other mammals
