Oliprevin
Oliprevin Brand names, Oliprevin Analogs
Oliprevin Brand Names Mixture
- No information avaliable
Oliprevin Chemical_Formula
C23H36O7
Oliprevin RX_link
http://www.rxlist.com/cgi/generic/pravast.htm
Oliprevin fda sheet
Oliprevin msds (material safety sheet)
Oliprevin Synthesis Reference
A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)
Oliprevin Molecular Weight
424.528 g/mol
Oliprevin Melting Point
326oC
Oliprevin H2O Solubility
2464mg/L
Oliprevin State
Solid
Oliprevin LogP
2.613
Oliprevin Dosage Forms
Tablet
Oliprevin Indication
For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.
Oliprevin Pharmacology
Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.
Oliprevin Absorption
Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.
Oliprevin side effects and Toxicity
Rhabdomyolysis; LD50=mg/kg (orally in rat)
Oliprevin Patient Information
Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.
Oliprevin Organisms Affected
Humans and other mammals
