Octatropine
Octatropine Brand names, Octatropine Analogs
Octatropine Brand Names Mixture
- No information avaliable
Octatropine Chemical_Formula
C17H32BrNO2
Octatropine RX_link
No information avaliable
Octatropine fda sheet
Octatropine msds (material safety sheet)
Octatropine Synthesis Reference
No information avaliable
Octatropine Molecular Weight
362.346 g/mol
Octatropine Melting Point
329 oC
Octatropine H2O Solubility
1600 mg/L
Octatropine State
Solid
Octatropine LogP
0.60
Octatropine Dosage Forms
Tablet (oral, 50mg)
Octatropine Indication
For use in conjunction with antacids or histamine H2-receptor antagonists in the treatment of peptic ulcer, to reduce further gastric acid secretion and delay gastric emptying.
Octatropine Pharmacology
Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant action on the bile ducts and gallbladder. In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate. Larger doses are required to decrease motility of the gastrointestinal and urinary tracts and to inhibit gastric acid secretion.
Octatropine Absorption
Gastrointestinal absorption is poor and irregular. Total absorption after an oral dose is about 10 to 25%.
Octatropine side effects and Toxicity
No information avaliable
Octatropine Patient Information
Octatropine Organisms Affected
Humans and other mammals
