Norpace
Norpace Brand names, Norpace Analogs
Norpace Brand Names Mixture
- No information avaliable
Norpace Chemical_Formula
C21H29N3O
Norpace RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Norpace fda sheet
Norpace msds (material safety sheet)
Norpace Synthesis Reference
No information avaliable
Norpace Molecular Weight
339.475 g/mol
Norpace Melting Point
94.5-95 oC
Norpace H2O Solubility
44.9 mg/L
Norpace State
Solid
Norpace LogP
3.972
Norpace Dosage Forms
Capsule; Tablet (extended-release)
Norpace Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Norpace Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Norpace Absorption
Nearly complete
Norpace side effects and Toxicity
LD50=580 mg/kg in rats
Norpace Patient Information
No information avaliable
Norpace Organisms Affected
Humans and other mammals
