Nitrendipine, Pharma en es it fr

Nitrendipine, Pharma Brand names, Nitrendipine, Pharma Analogs

Nitrendipine, Pharma Brand Names Mixture

  • No information avaliable

Nitrendipine, Pharma Chemical_Formula

C18H20N2O6

Nitrendipine, Pharma RX_link

No information avaliable

Nitrendipine, Pharma fda sheet

Nitrendipine, Pharma msds (material safety sheet)

Nitrendipine, Pharma Synthesis Reference

H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934

Nitrendipine, Pharma Molecular Weight

360.361 g/mol

Nitrendipine, Pharma Melting Point

156-160 oC

Nitrendipine, Pharma H2O Solubility

Insoluble

Nitrendipine, Pharma State

Solid

Nitrendipine, Pharma LogP

2.756

Nitrendipine, Pharma Dosage Forms

No information avaliable

Nitrendipine, Pharma Indication

For the treatment of mild to moderate hypertension

Nitrendipine, Pharma Pharmacology

Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Nitrendipine, Pharma Absorption

No information avaliable

Nitrendipine, Pharma side effects and Toxicity

No information avaliable

Nitrendipine, Pharma Patient Information

No information avaliable

Nitrendipine, Pharma Organisms Affected

Humans and other mammals