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Nitrendipin Brand names, Nitrendipin Analogs

Nitrendipin Brand Names Mixture

  • No information avaliable

Nitrendipin Chemical_Formula

C18H20N2O6

Nitrendipin RX_link

No information avaliable

Nitrendipin fda sheet

Nitrendipin msds (material safety sheet)

Nitrendipin Synthesis Reference

H. Meyar et al., Ger. pat 2117571; eidem, US pat. 3799934

Nitrendipin Molecular Weight

360.361 g/mol

Nitrendipin Melting Point

156-160 oC

Nitrendipin H2O Solubility

Insoluble

Nitrendipin State

Solid

Nitrendipin LogP

2.756

Nitrendipin Dosage Forms

No information avaliable

Nitrendipin Indication

For the treatment of mild to moderate hypertension

Nitrendipin Pharmacology

Nitrendipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nitrendipine is similar to other peripheral vasodilators. Nitrendipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum. The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.

Nitrendipin Absorption

No information avaliable

Nitrendipin side effects and Toxicity

No information avaliable

Nitrendipin Patient Information

No information avaliable

Nitrendipin Organisms Affected

Humans and other mammals