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Neoperidole Brand names, Neoperidole Analogs

Neoperidole Brand Names Mixture

  • No information avaliable

Neoperidole Chemical_Formula

C28H29F2N3O

Neoperidole RX_link

http://www.rxlist.com/cgi/generic3/orap.htm

Neoperidole fda sheet

Neoperidole msds (material safety sheet)

Neoperidole MSDS

Neoperidole Synthesis Reference

No information avaliable

Neoperidole Molecular Weight

461.546 g/mol

Neoperidole Melting Point

214-218 oC

Neoperidole H2O Solubility

10 mg/L

Neoperidole State

Solid

Neoperidole LogP

5.761

Neoperidole Dosage Forms

Tablet

Neoperidole Indication

Used for the suppression of motor and phonic tics in patients with Tourette's Disorder who have failed to respond satisfactorily to standard treatment.

Neoperidole Pharmacology

Pimozide is an orally active antipsychotic drug product which shares with other antipsychotics the ability to blockade dopaminergic receptors on neurons in the central nervous system. However, receptor blockade is often accompanied by a series of secondary alterations in central dopamine metabolism and function which may contribute to both pimozide's therapeutic and untoward effects. In addition, pimozide, in common with other antipsychotic drugs, has various effects on other central nervous system receptor systems which are not fully characterized. Pimozide also has less potential for inducing sedation and hypotension as it has more specific dopamine receptor blocking activity than other neuroleptic agents (and is therefore a suitable alternative to haloperidol).

Neoperidole Absorption

Greater than 50% absorption after oral administration. Serum peak appears 6-8 hours post ingestion.

Neoperidole side effects and Toxicity

LD50 = 1100 mg/kg (rat, oral), 228 mg/kg (mouse, oral)

Neoperidole Patient Information

No information avaliable

Neoperidole Organisms Affected

Humans and other mammals