Nebralin en es it fr

Nebralin Brand names, Nebralin Analogs

Nebralin Brand Names Mixture

  • No information avaliable

Nebralin Chemical_Formula

C32H41NO2

Nebralin RX_link

http://www.rxlist.com/cgi/generic/terfen.htm

Nebralin fda sheet

Nebralin msds (material safety sheet)

Nebralin Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Nebralin Molecular Weight

471.673 g/mol

Nebralin Melting Point

146.5-148.5oC

Nebralin H2O Solubility

10 mg/L

Nebralin State

Solid

Nebralin LogP

7.784

Nebralin Dosage Forms

Oral tablets

Nebralin Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Nebralin Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Nebralin Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Nebralin side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)

Nebralin Patient Information

Nebralin Organisms Affected

Humans and other mammals