Nateglinide
Nateglinide Brand names, Nateglinide Analogs
Nateglinide Brand Names Mixture
- No information avaliable
Nateglinide Chemical_Formula
C19H27NO3
Nateglinide RX_link
http://www.rxlist.com/cgi/generic2/nateglinide.htm
Nateglinide fda sheet
Nateglinide msds (material safety sheet)
Nateglinide Synthesis Reference
No information avaliable
Nateglinide Molecular Weight
317.423 g/mol
Nateglinide Melting Point
No information avaliable
Nateglinide H2O Solubility
Practically insoluble
Nateglinide State
Solid
Nateglinide LogP
3.824
Nateglinide Dosage Forms
Tablets (60, 120 mg)
Nateglinide Indication
For use as monotherapy to lower blood glucose in patients with Type 2 diabetes (non-insulin dependent diabetes mellitus, NIDDM) whose hyperglycemia cannot be adequately controlled by diet and physical exercise and who have not been chronically treated with other anti-diabetic agents. Also indicated for use in combination with metformin.
Nateglinide Pharmacology
Nateglinide is an amino-acid derivative that lowers blood glucose levels by stimulating insulin secretion from the pancreas. This action is dependent upon functioning beta-cells in the pancreatic islets.
Nateglinide Absorption
Rapidly absorbed following oral administration prior to a meal, absolute bioavailability is estimated to be approximately 73%.
Nateglinide side effects and Toxicity
An overdose may result in an exaggerated glucose-lowering effect with the development of hypoglycemic symptoms.
Nateglinide Patient Information
Nateglinide Organisms Affected
Humans and other mammals
