Naloxone

• Antinarcotic Agents
• Depressants
• Opiate Antagonists
• ATC:V03AB15

• EN 1530 Base
• L-Naloxone
• N-Allylnoroxymorphone
• Nalone
• Nalossone [Dcit]
• Naloxona [Inn-Spanish]
• Naloxone HCl
• Naloxonum [Inn-Latin]
• Narcan
• Narcanti
• Narcon
• Narcotic Antagonist

• No information avaliable

C₁₉H₂₁NO₄

http://www.rxlist.com/cgi/generic3/naloxone.htm

Naloxone MSDS

No information avaliable

327.374 g/mol

200 - 205 ^oC

Soluble

Solid

1.464

Liquid

For the complete or partial reversal of narcotic depression, including respiratory depression, induced by opioids including natural and synthetic narcotics, propoxyphene, methadone and the narcotic-antagonist analgesics: nalbuphine, pentazocine and butorphanol.

Naloxone is an opiate antagonist and prevents or reverses the effects of opioids including respiratory depression, sedation and hypotension. Also, it can reverse the psychotomimetic and dysphoric effects of agonist-antagonists such as pentazocine. Naloxone is an essentially pure narcotic antagonist, i.e., it does not possess the "agonistic" or morphine-like properties characteristic of other narcotic antagonists; naloxone does not produce respiratory depression, psychotomimetic effects or pupillary constriction. In the absence of narcotics or agonistic effects of other narcotic antagonists, it exhibits essentially no pharmacologic activity.

Well absorbed following intramuscular injection.

No information avaliable

No information avaliable

Humans and other mammals