Nafcillin sodium for injection

Nafcillin sodium for injection Brand names, Nafcillin sodium for injection Analogs

Nafcillin sodium for injection Brand Names Mixture

No information avaliable

Nafcillin sodium for injection Chemical_Formula

C₃₃H₄₇NO₁₃

Nafcillin sodium for injection RX_link

http://www.rxlist.com/cgi/generic2/natamycin.htm

Nafcillin sodium for injection fda sheet

Nafcillin sodium for injection msds (material safety sheet)

Nafcillin sodium for injection Synthesis Reference

No information avaliable

Nafcillin sodium for injection Molecular Weight

665.725 g/mol

Nafcillin sodium for injection Melting Point

290 ^oC

Nafcillin sodium for injection H₂O Solubility

4100 mg/L

Nafcillin sodium for injection State

Solid

Nafcillin sodium for injection LogP

0.495

Nafcillin sodium for injection Dosage Forms

Ophthalmic suspension (5%)

Nafcillin sodium for injection Indication

For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.

Nafcillin sodium for injection Pharmacology

Natamycin is an antifungal drug for topical ophthalmic administration. It is a tetraene polyene antibiotic derived from Streptomyces natalensis. It possesses in vitro activity against a variety of yeast and filamentous fungi, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. Although the activity against fungi is dose-related, natamycin is predominantly fungicidal. Natamycin is not effective in vitro against gram-positive or gram-negative bacteria. Topical administration appears to produce effective concentrations of natamycin within the corneal stroma but not in intraocular fluid.

Nafcillin sodium for injection Absorption

Systemic absorption should not be expected following topical administration, and as with other polyene antibiotics, absorption from the gastrointestinal tract is very poor.

Nafcillin sodium for injection side effects and Toxicity