Nafcillin Sodium

Nafcillin Sodium Brand names, Nafcillin Sodium Analogs

Nafcillin Sodium Brand Names Mixture

No information avaliable

Nafcillin Sodium Chemical_Formula

C₃₃H₄₇NO₁₃

Nafcillin Sodium RX_link

http://www.rxlist.com/cgi/generic2/natamycin.htm

Nafcillin Sodium fda sheet

Nafcillin Sodium msds (material safety sheet)

Nafcillin Sodium Synthesis Reference

No information avaliable

Nafcillin Sodium Molecular Weight

665.725 g/mol

Nafcillin Sodium Melting Point

290 ^oC

Nafcillin Sodium H₂O Solubility

4100 mg/L

Nafcillin Sodium State

Solid

Nafcillin Sodium LogP

0.495

Nafcillin Sodium Dosage Forms

Ophthalmic suspension (5%)

Nafcillin Sodium Indication

For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.

Nafcillin Sodium Pharmacology

Natamycin is an antifungal drug for topical ophthalmic administration. It is a tetraene polyene antibiotic derived from Streptomyces natalensis. It possesses in vitro activity against a variety of yeast and filamentous fungi, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. Although the activity against fungi is dose-related, natamycin is predominantly fungicidal. Natamycin is not effective in vitro against gram-positive or gram-negative bacteria. Topical administration appears to produce effective concentrations of natamycin within the corneal stroma but not in intraocular fluid.

Nafcillin Sodium Absorption

Systemic absorption should not be expected following topical administration, and as with other polyene antibiotics, absorption from the gastrointestinal tract is very poor.

Nafcillin Sodium side effects and Toxicity