Nafarelin acetate
Nafarelin acetate Brand names, Nafarelin acetate Analogs
Nafarelin acetate Brand Names Mixture
- No information avaliable
Nafarelin acetate Chemical_Formula
C14H14O3
Nafarelin acetate RX_link
http://www.rxlist.com/cgi/generic/naproxsod.htm
Nafarelin acetate fda sheet
Nafarelin acetate msds (material safety sheet)
Nafarelin acetate Synthesis Reference
No information avaliable
Nafarelin acetate Molecular Weight
230.259 g/mol
Nafarelin acetate Melting Point
153 oC
Nafarelin acetate H2O Solubility
15.9 mg/L
Nafarelin acetate State
Solid
Nafarelin acetate LogP
3.313
Nafarelin acetate Dosage Forms
Suppository; Suspension; Tablet; Tablet (enteric-coated); Tablet (extended-release)
Nafarelin acetate Indication
For the treatment of rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, tendinitis, bursitis, and acute gout. Also for the relief of mild to moderate pain and the treatment of primary dysmenorrhea.
Nafarelin acetate Pharmacology
Naproxen is a member of the arylacetic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Naproxen has analgesic and antipyretic properties. As with other NSAIDs, its mode of action is not fully understood; however, its ability to inhibit prostaglandin synthesis may be involved in the anti-inflammatory effect.
Nafarelin acetate Absorption
Naproxen itself is rapidly and completely absorbed from the GI tract with an in vivo bioavailability of 95%. Although naproxen itself is well absorbed, the sodium salt form is more rapidly absorbed resulting in higher peak plasma levels for a given dose. Food causes a slight decrease in the rate absorption.
Nafarelin acetate side effects and Toxicity
ORAL (LD50): Acute: 248 mg/kg [Rat]. 360 mg/kg [Mouse]. Symptoms of overdose include drowsiness, heartburn, indigestion, nausea, and vomiting.
Nafarelin acetate Patient Information
Nafarelin acetate Organisms Affected
Humans and other mammals
