NDGA

Category

NDGA




Useful info

NDGA Brand names, NDGA Analogs

NDGA Brand Names Mixture

  • No information avaliable

    • NDGA Chemical_Formula

    C22H30O3

    NDGA RX_link

    http://www.rxlist.com/cgi/generic4/megace_es.htm

    NDGA fda sheet

    NDGA FDA

    NDGA msds (material safety sheet)

    NDGA MSDS

    NDGA Synthesis Reference

    No information avaliable

    NDGA Molecular Weight

    342.472 g/mol

    NDGA Melting Point

    218.0-220.0oC

    NDGA H2O Solubility

    2 µg/mL (at 37°C for the acetate salt)

    NDGA State

    Solid

    NDGA LogP

    3.123

    NDGA Dosage Forms

    Oral suspension containing 125 mg of megestrol acetate per mL; Tablet

    NDGA Indication

    For the treatment of anorexia, cachexia, or an unexplained, significant weight loss in patients with a diagnosis of acquired immunodeficiency syndrome (AIDS). Also used to treat breast cancer, endometrial cancer, and prostate cancer in Canada and some other countries.

    NDGA Pharmacology

    Megestrol is a synthetic progestin and has the same physiologic effects as natural progesterone. The precise mechanism of megestrol’s antianorexic and anticachetic effects is unknown. Initially developed as a contraceptive, it was first evaluated in breast cancer treatment in 1967.

    NDGA Absorption

    Variable, but well absorbed orally.

    NDGA Toxicity

    No serious unexpected side effects have resulted from studies involving megestrol acetate oral suspension administered in dosages as high as 1200 mg/day.

    NDGA Patient Information

    No information avaliable

    NDGA Organisms Affected

    Humans and other mammals