Myolin

Myolin Brand names, Myolin Analogs

Myolin Brand Names Mixture

No information avaliable

Myolin Chemical_Formula

C₁₈H₂₃NO

Myolin RX_link

http://www.rxlist.com/cgi/generic/orphen.htm

Myolin fda sheet

Myolin FDA

Myolin msds (material safety sheet)

Myolin MSDS

Myolin Synthesis Reference

No information avaliable

Myolin Molecular Weight

269.381 g/mol

Myolin Melting Point

156-157 ^oC

Myolin H₂O Solubility

Sparingly soluble in water

Myolin State

Solid

Myolin LogP

4.034

Myolin Dosage Forms

Tablet (extended-release)

Myolin Indication

Indicated for the treatment of Parkinson's disease.

Myolin Pharmacology

Orphenadrine is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. Orphenadrine is an anticholinergic with a predominantly central effect and only a weak peripheral effect. In addition, it has mild antihistaminic and local anaesthetic properties. Parkinson's syndrome is the consequence of a disturbed balance between cholinergic and dopaminergic neurotransmission in the basal ganglia caused by a decrease in dopamine. Orphenadrine restores the physiological equilibrium and has a favourable effect on the rigidity and tremor of Parkinson's disease and Parkinsonian syndromes. The effect is somewhat less on bradykinesia.

Myolin Absorption

Orphenadrine is almost completely absorbed in the gastrointestinal tract.

Myolin side effects and Toxicity

Oral, mouse LD₅₀ = 100 mg/kg; oral, rat LD₅₀ = 255 mg/kg

Myolin Patient Information