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Moricizine [USAN] Brand names, Moricizine [USAN] Analogs

Moricizine [USAN] Brand Names Mixture

  • No information avaliable

Moricizine [USAN] Chemical_Formula

C21H21N

Moricizine [USAN] RX_link

http://www.rxlist.com/cgi/generic2/naft.htm

Moricizine [USAN] fda sheet

Moricizine [USAN] msds (material safety sheet)

Moricizine_[USAN] MSDS

Moricizine [USAN] Synthesis Reference

No information avaliable

Moricizine [USAN] Molecular Weight

287.398 g/mol

Moricizine [USAN] Melting Point

No information avaliable

Moricizine [USAN] H2O Solubility

No information avaliable

Moricizine [USAN] State

Solid

Moricizine [USAN] LogP

5.62

Moricizine [USAN] Dosage Forms

Cream; Gel (1%)

Moricizine [USAN] Indication

For the topical treatment of tinea pedis, tinea cruris, and tinea corporis caused by the organisms Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans and Epidermophyton floccosum.

Moricizine [USAN] Pharmacology

Naftifine is a synthetic, broad spectrum, antifungal agent and allylamine derivative. The following in vitro data are available, but their clinical significance is unknown. Naftifine has been shown to exhibit fungicidal activity in vitro against a broad spectrum of organisms including Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Epidermophyton floccosum, and Microsporum canis, Microsporum audouini, and Microsporum gypseum; and fungistatic activity against Candida species including Candida albicans. However it is only used to treat the organisms listed in the indications.

Moricizine [USAN] Absorption

Following single topical applications of 3H-labeled naftifine gel 1% to the skin of healthy subjects, up to 4.2% of the applied dose was absorbed.

Moricizine [USAN] side effects and Toxicity

No information avaliable

Moricizine [USAN] Patient Information

No information avaliable

Moricizine [USAN] Organisms Affected

Yeast and other fungi