Mono-Kay
Category
Mono-Kay Brand names, Mono-Kay Analogs
Mono-Kay Brand Names Mixture
No information avaliable
Mono-Kay Chemical_Formula
C31H46O2
Mono-Kay RX_link
http://www.rxlist.com/cgi/generic3/phytonadione.htm
Mono-Kay fda sheet
Mono-Kay msds (material safety sheet)
Mono-Kay Synthesis Reference
No information avaliable
Mono-Kay Molecular Weight
450.696 g/mol
Mono-Kay Melting Point
-20 oC
Mono-Kay H2O Solubility
Insoluble in water
Mono-Kay State
Liquid
Mono-Kay LogP
8.841
Mono-Kay Dosage Forms
Liquid
Mono-Kay Indication
For the treatment of haemorrhagic conditions in infants, antidote for coumarin anticoagulants in hypoprothrombinaemia
Mono-Kay Pharmacology
Phytonadione is a vitamin, indicated in the treatment of coagulation disorders which are due to faulty formation of factors II, VII, IX and X when caused by vitamin K deficiency or interference with vitamin K activity. Phytonadione aqueous colloidal solution of vitamin K1 for parenteral injection, possesses the same type and degree of activity as does naturally-occurring vitamin K, which is necessary for the production via the liver of active prothrombin (factor II), proconvertin (factor VII), plasma thromboplastin component (factor IX), and Stuart factor (factor X).
Mono-Kay Absorption
Oral phytonadione is adequately absorbed from the gastrointestinal tract only if bile salts are present. After absorption, phytonadione is initially concentrated in the liver, but the concentration declines rapidly. Very little vitamin K accumulates in tissues.
Mono-Kay Toxicity
No information avaliable
Mono-Kay Patient Information
No information avaliable
Mono-Kay Organisms Affected
Humans and other mammals