Moexipril HCL en es it fr

Moexipril HCL Brand names, Moexipril HCL Analogs

Moexipril HCL Brand Names Mixture

  • No information avaliable

Moexipril HCL Chemical_Formula


Moexipril HCL RX_link

Moexipril HCL fda sheet

Moexipril HCL msds (material safety sheet)

Moexipril_HCL MSDS

Moexipril HCL Synthesis Reference

No information avaliable

Moexipril HCL Molecular Weight

1321.6344 g/mol

Moexipril HCL Melting Point

No information avaliable

Moexipril HCL H2O Solubility

No information avaliable

Moexipril HCL State


Moexipril HCL LogP

No information avaliable

Moexipril HCL Dosage Forms

Liquid; Metered-dose (aerosol)

Moexipril HCL Indication

For treatment of gonadotropin-dependent precocious puberty in children of both sexes and for the treatment of endometriosis.

Moexipril HCL Pharmacology

Nafarelin is a potent agonistic analog of gonadotropin-releasing hormone (GnRH). At the onset of administration, nafarelin stimulates the release of the pituitary gonadotropins, LH and FSH, resulting in a temporary increase of gonadal steroidogenesis. Repeated dosing abolishes the stimulatory effect on the pituitary gland. Twice daily administration leads to decreased secretion of gonadal steroids by about 4 weeks; consequently, tissues and functions that depend on gonadal steroids for their maintenance become quiescent. After nafarelin therapy is discontinued, pituitary and ovarian function normalize and estradiol serum concentrations increase to pretreatment levels. Recurrences of endometriosis are frequent after cessation of any hormonal therapy and after surgery that leaves the ovaries and/or uterus intact.

Moexipril HCL Absorption

Rapidly absorbed into the systemic circulation after intranasal administration. Bioavailability from a 400 µg dose averaged 2.8% (range 1.2 to 5.6%). Not absorbed after oral administration.

Moexipril HCL side effects and Toxicity

In experimental animals, a single subcutaneous administration of up to 60 times the recommended human dose (on a µg/kg basis, not adjusted for bioavailability) had no adverse effects. At present, there is no clinical evidence of adverse effects following overdosage of GnRH analogs.

Moexipril HCL Patient Information

Moexipril HCL Organisms Affected

Humans and other mammals