Mivacurium

• Neuromuscular Nondepolarizing Agents
• ATC:M03AC10

• Mycamine

• No information avaliable

C₅₈H₈₀N₂O₁₄+₂

http://www.rxlist.com/cgi/generic3/mivacur.htm

Mivacurium FDA

Mivacurium MSDS

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1029.26 g/mol

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Liquid

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Solution (sterile, non-pyrogenic, with pH 3.5 to 5.0 containing mivacurium chloride equivalent to 2 mg/mL mivacurium in water for injection)

For inpatients and outpatients, as an adjunct to general anesthesia, to facilitate tracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation.

Mivacurium is a short-acting, nondepolarizing skeletal neuromuscular blocking agent which is hydrolyzed by plasma cholinesterase. Mivacurium results in a blockade of neuromuscular transmission by binding competitively with cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine. The neuromuscular block produced by mivacurium is readily antagonized by anticholinesterase agents. The deeper the level of neuromuscular block at reversal, the longer the time required for recovery of neuromuscular function and the greater the dose of anticholinesterase agent required. Because spontaneous recovery after mivacurium is rapid, routine reversal may not always result in a clinical benefit.

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Overdosage with neuromuscular blocking agents may result in neuromuscular block beyond the time needed for surgery and anesthesia.

Humans and other mammals