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Mitoxan Brand names, Mitoxan Analogs

Mitoxan Brand Names Mixture

  • No information avaliable

Mitoxan Chemical_Formula


Mitoxan RX_link

Mitoxan fda sheet

Mitoxan msds (material safety sheet)

Mitoxan MSDS

Mitoxan Synthesis Reference

No information avaliable

Mitoxan Molecular Weight

261.085 g/mol

Mitoxan Melting Point

39-41 oC

Mitoxan H2O Solubility

3780 mg/L

Mitoxan State


Mitoxan LogP


Mitoxan Dosage Forms

Powder for constitution and administration by intravenous infusion

Mitoxan Indication

For third line chemotherapy of germ cell testicular cancer. It should ordinarily be used in combination with a prophylactic agent for hemorrhagic cystitis, such as mesna.

Mitoxan Pharmacology

Ifosfamide selectively inhibits the synthesis of deoxyribonucleic acid (DNA). The guanine and cytosine content correlates with the degree of ifosfamide-induced cross-linking. At high concentrations of the drug, cellular RNA and protein synthesis are also suppressed.

Mitoxan Absorption

No information avaliable

Mitoxan side effects and Toxicity

LD50 (mouse) = 390-1005 mg/kg, LD50 (rat) = 150-190 mg/kg. Side effects include nausea, vomiting and myelosuppression. Toxic effects include central nervous system toxicity (confusion, hallucinations) and urotoxic effects (cystitis, blood in urine).

Mitoxan Patient Information

No information avaliable

Mitoxan Organisms Affected

Humans and other mammals