Mirtazapine
Mirtazapine Brand names, Mirtazapine Analogs
Mirtazapine Brand Names Mixture
- No information avaliable
Mirtazapine Chemical_Formula
C17H19N3
Mirtazapine RX_link
http://www.rxlist.com/cgi/generic/mirtaz.htm
Mirtazapine fda sheet
Mirtazapine msds (material safety sheet)
Mirtazapine Synthesis Reference
W. J. Van der Burg, U.S. Pat. 4,062,848 (1977)
Mirtazapine Molecular Weight
265.353 g/mol
Mirtazapine Melting Point
114-116oC
Mirtazapine H2O Solubility
Slight
Mirtazapine State
Solid
Mirtazapine LogP
2.369
Mirtazapine Dosage Forms
Tablet; Tablet (orally disintegrating)
Mirtazapine Indication
For the treatment of major depressive disorder.
Mirtazapine Pharmacology
Mirtazapine, an antidepressant of the piperazinoazepine class, is a tetracyclic compound with an anxiolytic effect. Mirtazapine has fewer ADRs than tricyclic antidepressants and is better tolerated. Selective blockade of specific serotonin receptors by mirtazapine likey minimizes side effects typical of other antidepressants.
Mirtazapine Absorption
Rapid and complete, but, due to first-pass metabolism, absolute bioavailability is 50%.
Mirtazapine side effects and Toxicity
Symptoms of overdose include disorientation, drowsiness, impaired memory, and tachycardia. LD50=mg/kg (orally in rat).
Mirtazapine Patient Information
Mirtazapine Organisms Affected
Humans and other mammals
