Mingit en es it fr

Mingit Brand names, Mingit Analogs

Mingit Brand Names Mixture

  • No information avaliable

Mingit Chemical_Formula

C13H12Cl2O4

Mingit RX_link

http://www.rxlist.com/cgi/generic3/edecrin.htm

Mingit fda sheet

Mingit FDA

Mingit msds (material safety sheet)

Mingit MSDS

Mingit Synthesis Reference

No information avaliable

Mingit Molecular Weight

303.137 g/mol

Mingit Melting Point

122.5 oC

Mingit H2O Solubility

No information avaliable

Mingit State

Solid

Mingit LogP

3.414

Mingit Dosage Forms

Tablet (25, 50 mg); Powder for solution

Mingit Indication

For the treatment of high blood pressure and edema caused by diseases like congestive heart failure, liver failure, and kidney failure.

Mingit Pharmacology

Ethacrynic acid is a monosulfonamyl loop or high ceiling diuretic. Ethacrynic acid acts on the ascending limb of the loop of Henle and on the proximal and distal tubules. Urinary output is usually dose dependent and related to the magnitude of fluid accumulation. Water and electrolyte excretion may be increased several times over that observed with thiazide diuretics, since ethacrynic acid inhibits reabsorption of a much greater proportion of filtered sodium than most other diuretic agents. Therefore, ethacrynic acid is effective in many patients who have significant degrees of renal insufficiency. Ethacrynic acid has little or no effect on glomerular filtration or on renal blood flow, except following pronounced reductions in plasma volume when associated with rapid diuresis.

Mingit Absorption

Onset of action is rapid, usually within 30 minutes after an oral dose of ethacrynic acid or within 5 minutes after an intravenous injection of ethacrynic acid.

Mingit side effects and Toxicity

Overdosage may lead to excessive diuresis with electrolyte depletion.

Mingit Patient Information

No information avaliable

Mingit Organisms Affected

Humans and other mammals