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Microlut Brand names, Microlut Analogs

Microlut Brand Names Mixture

  • Lo-Femenal 21 Tablets (ethinyl estradiol + norgestrel)
  • Ovral 21 Tablets (ethinyl estradiol + norgestrel)
  • Ovral 28 Tablets (ethinyl estradiol + norgestrel)

Microlut Chemical_Formula

C21H28O2

Microlut RX_link

http://www.rxlist.com/cgi/generic/norgeth.htm

Microlut fda sheet

Microlut msds (material safety sheet)

Microlut Synthesis Reference

G. A. Smith, H. Smith, U.S. Pat. 3,959,322 (1976)

Microlut Molecular Weight

312.446 g/mol

Microlut Melting Point

206oC

Microlut H2O Solubility

No information avaliable

Microlut State

Solid

Microlut LogP

3.251

Microlut Dosage Forms

Tablet

Microlut Indication

Used as an oral contraceptive to prevent pregnancy

Microlut Pharmacology

Norgestrel is used as a female contraceptive. Norgestrel is a progestin or a synthetic form of the naturally occurring female sex hormone, progesterone. In a woman's normal menstrual cycle, an egg matures and is released from the ovaries (ovulation). The ovary then produces progesterone, preventing the release of further eggs and priming the lining of the womb for a possible pregnancy. If pregnancy occurs, progesterone levels in the body remain high, maintaining the womb lining. If pregnancy does not occur, progesterone levels in the body fall, resulting in a menstrual period. Norgestrel tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. This prevents the release of eggs from the ovaries.

Microlut Absorption

65%

Microlut side effects and Toxicity

Nausea, vomiting, and drowsiness/fatigue; Withdrawal bleeding; LD50=mg/kg (orally in rat)

Microlut Patient Information

PATIENT INFORMATION

WHEN TO START THE FIRST PACK OF PILLS

For the 21-day pill pack you have two choices of which day to start taking your first pack of
pills. (See DAY 1 START or SUNDAY START directions below.) Decide with your health-care
professional which is the best day for you. The 28-day pill pack accommodates a SUNDAY START only.
For either pill pack pick a time of day which will be easy to remember.

DAY 1 START

These instructions are for the 21-day pill pack only. The 28-day pill pack does not accommodate a
DAY 1 START dosage regimen.

1. Take the first "active" white pill of the first pack during the first 24 hours of your period.

2. You will not need to use a back-up nonhormonal method of birth control, since you are starting
the pill at the beginning of your period.

SUNDAY START

These instructions are for either the 21-day or the 28-day pill pack.

1. Take the first "active" white pill of the first pack on the Sunday after your period starts, even
if you are still bleeding. If your period begins on Sunday, start the pack that same day.

2. Use a nonhormonal method of birth control (such as condoms and/or spermicide) as a backup method if
you have sex anytime from the Sunday you start your first pack until the next Sunday (7 days).

WHAT TO DO DURING THE MONTH

1. TAKE ONE PILL AT THE SAME TIME EVERY DAY UNTIL THE PACK IS EMPTY.

Do not skip pills even if you are spotting or bleeding between monthly periods or feel sick to your
stomach (nausea).

Do not skip pills even if you do not have sex very often.

2. WHEN YOU FINISH A PACK OR SWITCH YOUR BRAND OF PILLS:

21 pills: Wait 7 days to start the next pack. You will probably have your period during that week. Be
sure that no more than 7 days pass between 21-day packs.

28 pills: Start the next pack on the day after your last "reminder" pill. Do not wait any days between
packs.

WHAT TO DO IF YOU MISS PILLS

The pill may not be as effective if you miss white "active" pills, and particularly if you miss the first
few or the last few white "active" pills in a pack.

If you MISS 1 white "active" pill:

1. Take it as soon as you remember. Take the next pill at your regular time. This means you may take 2 pills
in 1 day.

2. You COULD BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use a nonhormonal
birth-control method (such as condoms and/or spermicide) as a backup for those 7 days.

If you MISS 2 white "active" pills in a row in WEEK 1 OR WEEK 2 of your pack:

1. Take 2 pills on the day you remember and 2 pills the next day.

2. Then take 1 pill a day until you finish the pack.

3. You COULD BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use a nonhormonal
birth-control method (such as condoms and/or spermicide) as a backup for those 7 days.

If you MISS 2 white "active" pills in a row in THE 3rd WEEK:

The Day 1 Starter instructions are for the 21-day pill pack only. The 28-day pill pack does not accommodate a
DAY 1 START dosage regimen. The Sunday Starter instructions are for either the 21-day or 28-day pill pack.

1. If you are a Day 1 Starter:

THROW OUT the rest of the pill pack and start a new pack that same day.

If you are a Sunday Starter:

Keep taking 1 pill every day until Sunday.

On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day.

2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a
row, call your health-care professional because you might be pregnant.

3. You COULD BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use a nonhormonal
birth-control method (such as condoms and/or spermicide) as a backup for those 7 days.

If you MISS 3 OR MORE white "active" pills in a row (during the first 3 weeks):

The Day 1 Starter instructions are for the 21-day pill pack only. The 28-day pill pack does not accommodate a
DAY 1 START dosage regimen. The Sunday Starter instructions are for either the 21-day or 28-day pill pack.

1. If you are a Day 1 Starter:

THROW OUT the rest of the pill pack and start a new pack that same day.

If you are a Sunday Starter:

Keep taking 1 pill every day until Sunday.

On Sunday, THROW OUT the rest of the pack and start a new pack of pills that same day.

2. You may not have your period this month but this is expected. However, if you miss your period 2 months in a
row, call your health-care professional because you might be pregnant.

3. You COULD BECOME PREGNANT if you have sex in the 7 days after you miss pills. You MUST use a nonhormonal
birth-control method (such as condoms and/or spermicide) as a backup for those 7 days.

A REMINDER FOR THOSE ON 28-DAY PACKS

If you forget any of the 7 pink "reminder" pills in Week 4:

THROW AWAY the pills you missed.

Keep taking 1 pill each day until the pack is empty.

You do not need a back-up nonhormonal birth-control method if you start your next pack on time.

FINALLY, IF YOU ARE STILL NOT SURE WHAT TO DO ABOUT THE PILLS YOU HAVE MISSED

Use a BACK-UP NONHORMONAL BIRTH-CONTROL METHOD anytime you have sex.

KEEP TAKING ONE PILL EACH DAY until you can reach your health-care professional.

PREGNANCY DUE TO PILL FAILURE

The incidence of pill failure resulting in pregnancy is approximately 1% if taken every day as directed, but the
average failure rate is approximately 5% including women who do not always take the pill exactly as directed
without missing any pills. If you do become pregnant, the risk to the fetus is minimal, but you should stop
taking your pills and discuss the pregnancy with your health-care professional.

PREGNANCY AFTER STOPPING THE PILL

There may be some delay in becoming pregnant after you stop using oral contraceptives, especially if you had
irregular menstrual cycles before you used oral contraceptives. It may be advisable to postpone conception until
you begin menstruating regularly once you have stopped taking the pill and desire pregnancy.

There does not appear to be any increase in birth defects in newborn babies when pregnancy occurs soon after
stopping the pill.

If you do not desire pregnancy, you should use another method of birth control immediately after stopping the
oral contraceptive pill.

OVERDOSE

Overdosage may cause nausea, vomiting, and fatigue/drowsiness. Withdrawal bleeding may occur in females. In
case of overdosage, contact your health-care professional or pharmacist.

OTHER INFORMATION

Your health-care professional will take a medical and family history before prescribing oral contraceptives
and will examine you. The physical examination may be delayed to another time if you request it and the health-
care professional believes that it is appropriate to postpone it. You should be reexamined at least once a year.
Be sure to inform your health-care professional if there is a family history of any of the conditions listed
previously in this leaflet. Be sure to keep all appointments with your health-care professional, because this
is a time to determine if there are early signs of side effects of oral-contraceptive use.

Do not use the drug for any condition other than the one for which it was prescribed. This drug has been
prescribed specifically for you; do not give it to others who may want birth-control pills.

HEALTH BENEFITS FROM ORAL CONTRACEPTIVES

In addition to preventing pregnancy, use of oral contraceptives may provide certain benefits. They are:

Menstrual cycles may become more regular.

Blood flow during menstruation may be lighter, and less iron may be lost. Therefore, anemia due to iron
deficiency is less likely to occur.

Pain or other symptoms during menstruation may be encountered less frequently.

Ovarian cysts may occur less frequently.

Ectopic (tubal) pregnancy may occur less frequently.

Noncancerous cysts or lumps in the breast may occur less frequently.

Acute pelvic inflammatory disease may occur less frequently.

Oral-contraceptive use may provide some protection against developing two forms of cancer: cancer of the
ovaries and cancer of the lining of the uterus.

If you want more information about birth-control pills, ask your health-care professional or pharmacist. They
have a more technical leaflet called the Professional Labeling which you may wish to read.

Microlut Organisms Affected

Humans and other mammals