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Mevinolin Brand names, Mevinolin Analogs

Mevinolin Brand Names Mixture

  • No information avaliable

Mevinolin Chemical_Formula

C23H36O7

Mevinolin RX_link

http://www.rxlist.com/cgi/generic/pravast.htm

Mevinolin fda sheet

Mevinolin FDA

Mevinolin msds (material safety sheet)

Mevinolin Synthesis Reference

A. Terahara, M.Tanaka, U.S. Pat. 4,346,227(1982)

Mevinolin Molecular Weight

424.528 g/mol

Mevinolin Melting Point

326oC

Mevinolin H2O Solubility

2464mg/L

Mevinolin State

Solid

Mevinolin LogP

2.613

Mevinolin Dosage Forms

Tablet

Mevinolin Indication

For the treatment of hypercholesterolemia to reduce the risk of myocardial infarction.

Mevinolin Pharmacology

Pravastatin, an antilipemic agent, is used to treat primary hypercholesterolemia. Unlike lovastatin and simvastatin, pravastatin is relatively hydrophilic and does not require hydrolysis for activation.

Mevinolin Absorption

Average oral absorption of pravastatin is 34% and absolute bioavailability is 17%.

Mevinolin side effects and Toxicity

Rhabdomyolysis; LD50=mg/kg (orally in rat)

Mevinolin Patient Information

Patients should be advised to report promptly unexplained muscle pain, tenderness or weakness, particularly if accompanied by malaise or fever.

Mevinolin Organisms Affected

Humans and other mammals