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Metolazona [INN-Spanish] Brand names, Metolazona [INN-Spanish] Analogs

Metolazona [INN-Spanish] Brand Names Mixture

  • No information avaliable

Metolazona [INN-Spanish] Chemical_Formula

C18H14Cl4N2O

Metolazona [INN-Spanish] RX_link

http://www.rxlist.com/cgi/generic2/micon.htm

Metolazona [INN-Spanish] fda sheet

Metolazona_[INN-Spanish] FDA

Metolazona [INN-Spanish] msds (material safety sheet)

Metolazona_[INN-Spanish] MSDS

Metolazona [INN-Spanish] Synthesis Reference

No information avaliable

Metolazona [INN-Spanish] Molecular Weight

416.127 g/mol

Metolazona [INN-Spanish] Melting Point

159 - 163 oC

Metolazona [INN-Spanish] H2O Solubility

1g/100mL (20°C)

Metolazona [INN-Spanish] State

Solid

Metolazona [INN-Spanish] LogP

6.02

Metolazona [INN-Spanish] Dosage Forms

Topical cream (2%); Vaginal cream (2%); Vaginal suppositories (100mg, 200mg)

Metolazona [INN-Spanish] Indication

For topical application in the treatment of tinea pedis (athlete’s foot), tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum, in the treatment of cutaneous candidiasis (moniliasis), and in the treatment of tinea versicolor.

Metolazona [INN-Spanish] Pharmacology

Miconazole is an anti-fungal medication related to fluconazole (Diflucan), ketoconazole (Nizoral), itraconazole (Sporanox), and clotrimazole (Lotrimin, Mycelex). It is used either on the skin or in the vagina for fungal infections. Miconazole was approved by the FDA in 1974. Miconazole prevents fungal organisms from producing vital substances required for growth and function. This medication is effective only for infections caused by fungal organisms. It will not work for bacterial or viral infections.

Metolazona [INN-Spanish] Absorption

No information avaliable

Metolazona [INN-Spanish] side effects and Toxicity

Oral, mouse: LD50 = 3800 mg/kg; Oral, rat: LD50 = 3 gm/kg. Ingestion of the amounts of the components contained in a tube of cream are unlikely to produce overdosage and toxic effects.

Metolazona [INN-Spanish] Patient Information

No information avaliable

Metolazona [INN-Spanish] Organisms Affected

Fungi, yeast and protozoans