Metoclopramide Hydrochloride en es it fr

Metoclopramide Hydrochloride Brand names, Metoclopramide Hydrochloride Analogs

Metoclopramide Hydrochloride Brand Names Mixture

  • No information avaliable

Metoclopramide Hydrochloride Chemical_Formula

C14H22ClN3O2

Metoclopramide Hydrochloride RX_link

http://www.rxlist.com/cgi/generic2/metoclo.htm

Metoclopramide Hydrochloride fda sheet

Metoclopramide_Hydrochloride FDA

Metoclopramide Hydrochloride msds (material safety sheet)

Metoclopramide_Hydrochloride MSDS

Metoclopramide Hydrochloride Synthesis Reference

Thominet, U.S. Pat. 3,177,252 (1965)

Metoclopramide Hydrochloride Molecular Weight

299.796 g/mol

Metoclopramide Hydrochloride Melting Point

147.25 oC

Metoclopramide Hydrochloride H2O Solubility

200 mg/L

Metoclopramide Hydrochloride State

Solid

Metoclopramide Hydrochloride LogP

2.464

Metoclopramide Hydrochloride Dosage Forms

Liquid; Syrup; Tablet

Metoclopramide Hydrochloride Indication

For the treatment of gastroesophageal reflux disease (GERD)

Metoclopramide Hydrochloride Pharmacology

Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.

Metoclopramide Hydrochloride Absorption

Rapidly and well absorbed (oral bioavailability 80±15.5%).

Metoclopramide Hydrochloride side effects and Toxicity

Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.

Metoclopramide Hydrochloride Patient Information

Metoclopramide Hydrochloride Organisms Affected

Humans and other mammals