Metoclopramide
Metoclopramide Brand names, Metoclopramide Analogs
- Apo-Metoclop
- Cerucal
- Clopra
- Clopra-Yellow
- Clopromate
- DEL
- Duraclamid
- Elieten
- Emetid
- Emperal
- Eucil
- Gastrese
- Gastro-Timelets
- Gastrobid
- Gastromax
- Gastronerton
- Gastrosil
- Gastrotablinen
- Gastrotem
- Imperan
- Maxeran
- Maxolon
- Meclopran
- Metaclopramide
- Metaclopromide
- Metamide
- Methochlopramide
- Methoclopramide
- Metochlopramide
- Metoclol
- Metoclopramida [Inn-Spanish]
- Metoclopramide Hcl
- Metoclopramide Hydrochloride
- Metoclopramide Intensol
- Metoclopramide Omega
- Metoclopramidum [Inn-Latin]
- Metocobil
- Metramid
- Moriperan
- Mygdalon
- Neu-Sensamide
- Nu-Metoclopramide
- Octamide
- Parmid
- Paspertin
- Peraprin
- Plasil
- Pms-Metoclopramide
- Pramiel
- Pramin
- Primperan
- Reclomide
- Reglan
- Reliveran
- Terperan
Metoclopramide Brand Names Mixture
- No information avaliable
Metoclopramide Chemical_Formula
C14H22ClN3O2
Metoclopramide RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Metoclopramide fda sheet
Metoclopramide msds (material safety sheet)
Metoclopramide Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Metoclopramide Molecular Weight
299.796 g/mol
Metoclopramide Melting Point
147.25 oC
Metoclopramide H2O Solubility
200 mg/L
Metoclopramide State
Solid
Metoclopramide LogP
2.464
Metoclopramide Dosage Forms
Liquid; Syrup; Tablet
Metoclopramide Indication
For the treatment of gastroesophageal reflux disease (GERD)
Metoclopramide Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Metoclopramide Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Metoclopramide side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Metoclopramide Patient Information
Metoclopramide Organisms Affected
Humans and other mammals
