Methylphenidate HCl
Methylphenidate HCl Brand names, Methylphenidate HCl Analogs
- 4311/B Ciba
- Calocain
- Centedein
- Centedrin
- Centedrine
- Centredin
- Concerta
- Focalin
- Focalin XR
- Methylphen
- Meridil
- Metadate
- Metadate CD
- Metadate ER
- Methyl phenidyl acetate
- Methylin
- Methylin ER
- Methylofenidan
- Methylphenidan
- Methylphenidate HCl
- Methylphenidate hydrochloride
- Methylphenidatum [Inn-Latin]
- Methylphenidylacetate hydrochloride
- Methypatch
- Metilfenidat hydrochloride
- Metilfenidato [Inn-Spanish]
- Metilfenidato [Italian]
- Phenidylate
- Plimasine
- PMS-Methylphenidate
- Riphenidate
- Ritalin
- Ritalin hydrochloride
- Ritalin LA
- Ritalin SR
- Ritalin-SR
- Ritaline
- Ritcher Works
Methylphenidate HCl Brand Names Mixture
- No information avaliable
Methylphenidate HCl Chemical_Formula
C14H19NO2
Methylphenidate HCl RX_link
http://www.rxlist.com/cgi/generic/methphen.htm
Methylphenidate HCl fda sheet
Methylphenidate HCl msds (material safety sheet)
Methylphenidate HCl Synthesis Reference
M. Hartmann, L. Panizzon, U.S. Pat. 2,507,631 (1950)
Methylphenidate HCl Molecular Weight
233.306 g/mol
Methylphenidate HCl Melting Point
224-226oC
Methylphenidate HCl H2O Solubility
1255mg/L
Methylphenidate HCl State
Solid
Methylphenidate HCl LogP
3.192
Methylphenidate HCl Dosage Forms
Tablets; Tablets (sustained release)
Methylphenidate HCl Indication
For use as an integral part of a total treatment program which typically includes other remedial measures (psychological, educational, social) for a stabilizing effect in children with a behavioral syndrome characterized by the following group of developmentally inappropriate symptoms: moderate-to-severe distractibility, short attention span, hyperactivity, emotional lability, and impulsivity.
Methylphenidate HCl Pharmacology
Methylphenidate is a central nervous system stimulant used most commonly in the treatment of attention-deficit disorders in children and for narcolepsy. Its mechanisms appear to be similar to those of dextroamphetamine.
Methylphenidate HCl Absorption
Readily absorbed in a biphasic manner. It reaches peak absorption at approximately two hours for the first phase and five hours for the second phase. Bioavailability is low (approximately 30%)
Methylphenidate HCl side effects and Toxicity
Symptoms of overdose include vomiting, agitation, tremors, hyperreflexia, muscle twitching, convulsions (may be followed by coma), euphoria, confusion, hallucinations, delirium, sweating, flushing, headache, hyperpyrexia, tachycardia, palpitations, cardiac arrhythmias, hypertension, mydriasis, and dryness of mucous membranes. LD50=190mg/kg (orally in mice)
Methylphenidate HCl Patient Information
Methylphenidate HCl Organisms Affected
Humans and other mammals
