PharmacyCodes



Methylaminopropyliminodibenzyl en es it fr

Methylaminopropyliminodibenzyl Brand names, Methylaminopropyliminodibenzyl Analogs

Methylaminopropyliminodibenzyl Brand Names Mixture

  • No information avaliable

Methylaminopropyliminodibenzyl Chemical_Formula

C18H22N2

Methylaminopropyliminodibenzyl RX_link

http://www.rxlist.com/cgi/generic2/desipram.htm

Methylaminopropyliminodibenzyl fda sheet

Methylaminopropyliminodibenzyl FDA

Methylaminopropyliminodibenzyl msds (material safety sheet)

Methylaminopropyliminodibenzyl MSDS

Methylaminopropyliminodibenzyl Synthesis Reference

No information avaliable

Methylaminopropyliminodibenzyl Molecular Weight

266.381 g/mol

Methylaminopropyliminodibenzyl Melting Point

214-218 oC

Methylaminopropyliminodibenzyl H2O Solubility

No information avaliable

Methylaminopropyliminodibenzyl State

Solid

Methylaminopropyliminodibenzyl LogP

3.87

Methylaminopropyliminodibenzyl Dosage Forms

Tablet

Methylaminopropyliminodibenzyl Indication

For relief of symptoms in various depressive syndromes, especially endogenous depression.

Methylaminopropyliminodibenzyl Pharmacology

Desipramine, a tertiary amine tricyclic antidepressant, is structurally related to both the skeletal muscle relaxant cyclobenzaprine and the thioxanthene antipsychotics such as thiothixene. Desipramine is used to treat depression, pain of neuropathic origin, attention_deficit hyperactivity disorder, functional enuresis in children, panic and phobic disorder, and to manage some eating disorders. Desipramine inhibits the re-uptake of noradrenaline at the noradrenergic nerve endings and the re-uptake of serotonin (5-hydroxy tryptamine) at the serotoninergic nerve endings in the central nervous system. These two effects are considered to be the likely base of the antidepressant effect of Desipramine. The drug also has a strong anticholinergic effect and serves as an antagonist on a1 and H1 receptors.

Methylaminopropyliminodibenzyl Absorption

Desipramine hydrochloride is rapidly and almost completely absorbed from the gastrointestinal tract. 90.5% (range 73-92%) of desipramine binds to plasma proteins.

Methylaminopropyliminodibenzyl side effects and Toxicity

Male mice: LD50 = 290 mg/kg, female rats: LD50 = 320 mg/kg

Methylaminopropyliminodibenzyl Patient Information

No information avaliable

Methylaminopropyliminodibenzyl Organisms Affected

Humans and other mammals