Methoxolone
Category
Methoxolone Brand names, Methoxolone Analogs
Methoxolone Brand Names Mixture
Methoxolone Chemical_Formula
C12H15NO3
Methoxolone RX_link
http://www.rxlist.com/cgi/generic/metax.htm
Methoxolone fda sheet
Methoxolone msds (material safety sheet)
Methoxolone Synthesis Reference
No information avaliable
Methoxolone Molecular Weight
221.252 g/mol
Methoxolone Melting Point
122 oC
Methoxolone H2O Solubility
No information avaliable
Methoxolone State
Solid
Methoxolone LogP
1.603
Methoxolone Dosage Forms
Tablets (400 mg round, pale rose tablet and an 800 mg oval, pink scored tablet)
Methoxolone Indication
For the treatment of painful musculoskeletal conditions
Methoxolone Pharmacology
Metaxalone is a skeletal muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. Metaxalone does not directly relax tense skeletal muscles in man.
Methoxolone Absorption
The absolute bioavailability of metaxalone from Skelaxin tablets is not known.
Methoxolone Toxicity
LD50=775mg/kg (Rat, oral); LD50=1690 mg/kg (Mouse, oral). When determining the LD50 in rats and mice, progressive sedation, hypnosis and finally respiratoryfailure were noted as the dosage increased. In dogs, no LD50 could be determined as the higher doses produced an emetic action in 15 to 30 minutes.
Methoxolone Patient Information
Patient Information:
Use Metaxalone with caution. It may affect driving, operating machinery or other hazarous activities. Metaxalone may increase the effects of alcohol
and other central nervous system depressants.
If you have liver problems or you are breast feeding, discuss with your doctor about the risks of taking the Metaxalone.
Methoxolone Organisms Affected
Humans and other mammals
