Methoclopramide
Methoclopramide Brand names, Methoclopramide Analogs
- Apo-Metoclop
- Cerucal
- Clopra
- Clopra-Yellow
- Clopromate
- DEL
- Duraclamid
- Elieten
- Emetid
- Emperal
- Eucil
- Gastrese
- Gastro-Timelets
- Gastrobid
- Gastromax
- Gastronerton
- Gastrosil
- Gastrotablinen
- Gastrotem
- Imperan
- Maxeran
- Maxolon
- Meclopran
- Metaclopramide
- Metaclopromide
- Metamide
- Methochlopramide
- Methoclopramide
- Metochlopramide
- Metoclol
- Metoclopramida [Inn-Spanish]
- Metoclopramide Hcl
- Metoclopramide Hydrochloride
- Metoclopramide Intensol
- Metoclopramide Omega
- Metoclopramidum [Inn-Latin]
- Metocobil
- Metramid
- Moriperan
- Mygdalon
- Neu-Sensamide
- Nu-Metoclopramide
- Octamide
- Parmid
- Paspertin
- Peraprin
- Plasil
- Pms-Metoclopramide
- Pramiel
- Pramin
- Primperan
- Reclomide
- Reglan
- Reliveran
- Terperan
Methoclopramide Brand Names Mixture
- No information avaliable
Methoclopramide Chemical_Formula
C14H22ClN3O2
Methoclopramide RX_link
http://www.rxlist.com/cgi/generic2/metoclo.htm
Methoclopramide fda sheet
Methoclopramide msds (material safety sheet)
Methoclopramide Synthesis Reference
Thominet, U.S. Pat. 3,177,252 (1965)
Methoclopramide Molecular Weight
299.796 g/mol
Methoclopramide Melting Point
147.25 oC
Methoclopramide H2O Solubility
200 mg/L
Methoclopramide State
Solid
Methoclopramide LogP
2.464
Methoclopramide Dosage Forms
Liquid; Syrup; Tablet
Methoclopramide Indication
For the treatment of gastroesophageal reflux disease (GERD)
Methoclopramide Pharmacology
Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.
Methoclopramide Absorption
Rapidly and well absorbed (oral bioavailability 80±15.5%).
Methoclopramide side effects and Toxicity
Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.
Methoclopramide Patient Information
Methoclopramide Organisms Affected
Humans and other mammals
