Methochlopramide en es it fr

Methochlopramide Brand names, Methochlopramide Analogs

Methochlopramide Brand Names Mixture

  • No information avaliable

Methochlopramide Chemical_Formula

C14H22ClN3O2

Methochlopramide RX_link

http://www.rxlist.com/cgi/generic2/metoclo.htm

Methochlopramide fda sheet

Methochlopramide FDA

Methochlopramide msds (material safety sheet)

Methochlopramide MSDS

Methochlopramide Synthesis Reference

Thominet, U.S. Pat. 3,177,252 (1965)

Methochlopramide Molecular Weight

299.796 g/mol

Methochlopramide Melting Point

147.25 oC

Methochlopramide H2O Solubility

200 mg/L

Methochlopramide State

Solid

Methochlopramide LogP

2.464

Methochlopramide Dosage Forms

Liquid; Syrup; Tablet

Methochlopramide Indication

For the treatment of gastroesophageal reflux disease (GERD)

Methochlopramide Pharmacology

Metoclopramide, although chemically related to procainamide, does not possess local anesthetic or antiarrhythmic properties. Metoclopramide is used to enhance GI motility, to treat diabetic gastroparesis, as an antinauseant, and to facilitate intubation of the small bowel during radiologic examination. Metoclopramide may be used to treat chemotherapy-induced emesis and as a radiosensitizing agents in the treatment of non-small cell lung carcinoma and glioblastomas in the future.

Methochlopramide Absorption

Rapidly and well absorbed (oral bioavailability 80±15.5%).

Methochlopramide side effects and Toxicity

Oral, mouse LD50: 280 mg/kg. Signs of overdose include drowsiness, disorientation, and extrapyramidal reactions.

Methochlopramide Patient Information

Methochlopramide Organisms Affected

Humans and other mammals